The Ameliorating Effects of Hyperbaric Oxygen Therapy (HBO2) on Quality Of Life in Patients with Maxillofacial Soft Tissue- and Osteo-Radionecrosis

TitleThe Ameliorating Effects of Hyperbaric Oxygen Therapy (HBO2) on Quality Of Life in Patients with Maxillofacial Soft Tissue- and Osteo-Radionecrosis
Publication TypeJournal Article
Year of Publication2008
AuthorsHarding, S, Courtney, D, Hodder, SC, Bryson, PJ
JournalInternational Journal of Oral & Maxillofacial Surgery
Volume37
Issue7
Start Page617
Abstract

BACKGROUND: Hyperbaric Oxygen (HBO2) is prescribed in two modes for patients who have maxillofacial soft tissue and/or osteoradionecrosis: conservatively (without surgery), for wound healing and preservation; or perioperatively for optimisation of tissue prior to surgery and for wound healing post operatively. The perioperative group can be further sub-divided into: 1) Prevention of radionecrosis due to dental clearance or implants 2) Removal of established necrotic tissues and where more surgery is required. Little research has been conducted investigating Quality of Life (QoL) in these groups. This research focuses on patients referred perioperatively. MATERIALS AND METHODS: From 2001 to 2005, 61 patients (48 males and 13 females; Mean age 56 years) were asked to complete questionnaires pre- and immediately post-HBO2 treatment. The questionnaires included the Medical Outcomes Short Form 36 (SF-36), Hospital Anxiety and Depression Scale (HADs), University of Washington Scale (UoW), European Organisation for research and treatment of cancer core (EORTC-C30) module and head and neck sub-module (H and N35). Patients underwent between 25 and 58 HBO2 therapies (Mean = 40, SD = 8.6). Scores between each time point were compared using Paired Samples T-Tests. RESULTS: Using the SF-36, significant improvements were seen in patients general functioning (P=0.034). Changes were also evident using the EORTC-C30 which showed significant improvement in general health, emotional functioning, pain and dyspnoea (P=0.023, P=0.031, P=0.042, P=0.023, respectively). The H and N35 identified ameliorations in teeth (P=0.017), and mouth opening (P=0.025). No significant differences were identified using HADs or UoW and there were no reported declines in QoL using any of the four questionnaires. CONCLUSIONS: This study shows HBO2 in combination with surgery improves patients QoL with respect to psychological and functional status. The authors are investigating the different patterns of changes within this group (patients having dental extractions or implants) and a similar patient group being treated with HBO2 conservatively.

Practical Implications

Pract taly summ